Endocrine Abstracts

Introduction: For the last 2 years we have been giving regular diabetes education sessions in conjunction with our hospital school, based around maths skills. These went well, but we wanted to develop these further, making them more patient centred. We gained a grant from the Diabetes Research and Wellness Foundation and designed a 4 day programme with ‘The Puppet Project’ and ‘WAC arts’. This was done very much in collabaration with our hospital school who...

Anamnesis: We report the case of a 54-year-old man who consulted for weight loss. He had been diagnosed with diabetes more than 20 years ago with good glycemic control (currently HbA1c 6.9%), no obesity, hypertension, or dyslipidaemia. A history of chronic pancreatitis and retinitis pigmentosa with eyelid ptosis. He maintains regular treatment with metformin, sitagliptin, repaglinide, ASA, Kreon and Pregabalin.Complementary testIn reference to the chief complaint, there had no...

Seasonal reproduction enables animals outside tropical regions to rear offspring in a favourable environment. Increasing day length triggers a hypothalamic relay involving thyrotropin, the type 2 deiodinase enzyme and thyroid hormone, which activates the hypothalamic-pituitary-gonadal axis to induce reproductive competence. Photoperiod regulates calcium metabolism and the egg-laying cycle in the Japanese quail (Coturnix japonica), and we hypothesised that activity of ...

Hypoparathyroidism may occur as: a hereditary syndromic disorder (e.g. Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED), Hypoparathyroidism Sensorineural Deafness and Renal Disease (HDR), Autosomal Dominant Hypoparathyroidism type 1 (ADH1), or ADH type 2 (ADH2), which are due to mutations of autoimmune regulator (AIRE), GATA binding protein 3 (GATA3), calcium-sensing receptor (CASR) and G-protein sub...

Background: Hyponatraemia (most commonly secondary to SIADH) is very common in cancer patients; it is associated with delays to oncology treatment and mortality.Aim: To evaluate the number of patients with hyponatraemia at a tertiary referral cancer centre and assess adherence to national recommendations for investigations and treatment.Methods: All biochemistry results (in-patient and outpatient) analys...

Case History: A 79 year old gentleman sustained a traumatic fracture of his left humerus in November 2016. Given his age and non-union of fracture, he was referred for a dual X-ray absorptiometry (DXA) scan in May 2017. This demonstrated markedly elevated bone mineral density (BMD) and subsequent investigation was performed.The patient has a past medical history of type 2 diabetes mellitus, hypertension, asthma and kidney stones. H...

Seasonal reproduction enables animals outside tropical regions to rear offspring in a favourable environment. Increasing day length triggers a hypothalamic relay involving thyrotropin, the type 2 deiodinase enzyme and thyroid hormone, which activates the hypothalamic-pituitary-gonadal axis to induce reproductive competence. Photoperiod regulates calcium metabolism and the egg-laying cycle in the Japanese quail (Coturnix japonica), and we hypothesised that activity of ...

Hypoparathyroidism may occur as: a hereditary syndromic disorder (e.g. Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED), Hypoparathyroidism Sensorineural Deafness and Renal Disease (HDR), Autosomal Dominant Hypoparathyroidism type 1 (ADH1), or ADH type 2 (ADH2), which are due to mutations of autoimmune regulator (AIRE), GATA binding protein 3 (GATA3), calcium-sensing receptor (CASR) and G-protein sub...

Background: Hyponatraemia (most commonly secondary to SIADH) is very common in cancer patients; it is associated with delays to oncology treatment and mortality.Aim: To evaluate the number of patients with hyponatraemia at a tertiary referral cancer centre and assess adherence to national recommendations for investigations and treatment.Methods: All biochemistry results (in-patient and outpatient) analys...

Case History: A 79 year old gentleman sustained a traumatic fracture of his left humerus in November 2016. Given his age and non-union of fracture, he was referred for a dual X-ray absorptiometry (DXA) scan in May 2017. This demonstrated markedly elevated bone mineral density (BMD) and subsequent investigation was performed.The patient has a past medical history of type 2 diabetes mellitus, hypertension, asthma and kidney stones. H...